Gastrointestinal Stromal Tumor (GIST) in India

Overview

Gastrointestinal Stromal Tumor (GIST) is a type of soft tissue sarcoma that originates in the digestive tract, primarily in the stomach and small intestine. Smaller GISTs often cause no health issues, but larger ones can lead to symptoms such as blood in stool or vomit. GISTs are more common in individuals aged 50 to 70 and are rare before the age of 40. It is an uncommon cancer that begins in special cells located in the wall of the digestive tract. Approximately 4,000 to 6,000 GIST cases are reported annually in the U.S. Genetic factors can increase the risk, especially in families where genetic mutations are common. Types of GIST include:

Procedure Details

Bleeding from the stomach may make vomit appear like coffee grounds and cause black, tarry stools. GISTs may block food passage (obstruction), rupture (causing holes in the GI tract), and can lead to emergency symptoms. They are often discovered during check-ups for unexplained abdominal pain, chronic anemia, or GI bleeding. Surgery is the most effective way to prevent GIST progression: Radiation and chemotherapy are not commonly needed but radiation can help control bleeding. Early-stage tumors can often be removed without harming surrounding organs

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